3,4-Difluoronitrobenzene is a unique chemical structure characterized by a benzene ring substituted with two fluorine atoms at the 3 and 4 positions, along with a nitro group (-NO2) attached to the ring. This compound exhibits notable reactivity due to the electron-withdrawing nature of both the fluorine and nitro groups. The presence of these substituents causes an increase in electrophilicity, making the benzene ring more susceptible to nucleophilic attack. Therefore, 3,4-difluoronitrobenzene serves as a valuable intermediate in the synthesis of various complex compounds, particularly those with pharmacological applications.
- Its physical properties include a melting point of around 50 degrees Celsius and a boiling point of approximately 190 degrees Celsius.
- Furthermore, it exhibits limited solubility in water but is miscible in common organic solvents.
The synthesis of 3,4-difluoronitrobenzene typically comprises a multi-step process which includes the nitration of fluorobenzene followed by precise fluorination. This compound has been widely studied due to its potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Synthesis and Properties of 3,4-Difluoronitrobenzene
3,4-Difluoronitrobenzene is a significant role in the realm of organic synthesis due to its unique structural characteristics. The synthesis of this compound can be achieved through various routes, with a commonly employed method involving the nitration of 1,2-difluorobenzene. This reaction typically utilizes a mixture of nitric acid and sulfuric acid as the nitrating agent, generating the desired 3,4-difluoronitrobenzene product.
The resulting compound exhibits distinct physicochemical properties that influence its reactivity and applications. Notably, the electron-withdrawing nature of the nitro group in 3,4-difluoronitrobenzene enhances its electrophilicity, making it susceptible to nucleophilic attack. This property renders it a versatile building block for the synthesis of complex organic molecules.
- Furthermore, the presence of fluorine atoms in the molecule contributes to its stability and dissolvability in various solvents.
CAS No. for 3,4-Difluoronitrobenzene: Identifying This Compound
When working with chemicals, accurately identifying them is crucial for safety and accurate results. A key tool in this process is the CAS Registry Number, a unique identifier assigned to every chemical compound. For 3,4-Difluoronitrobenzene, this number is critical for ensuring you are working with the correct substance.
The CAS No. for 3,4-Difluoronitrobenzene is 105387-96-3. This numerical identifier can be used to locate information about the compound in databases and source materials. Understanding its properties, hazards, and safe handling procedures is essential when dealing with this chemical.
Applications of 3,4-Difluoronitrobenzene in Research
3,4-Difluoronitrobenzene finds a wide variety of applications in research. Its unique configuration and chemical properties permit it to be utilized as a valuable intermediate in the synthesis of sophisticated organic compounds. Researchers exploit 3,4-difluoronitrobenzene for its adaptability in developing new materials with targeted properties. Furthermore, this substance functions as a important reagent in the study of physical processes. Its potential extend numerous research areas, including organic chemistry.
Safety Considerations for Handling 3,4-Difluoronitrobenzene
When working with 3,4-difluoronitrobenzene, it is critical to prioritize personal protection. This chemical can be dangerous if not managed properly. Always work in a well-ventilated region and don appropriate protective clothing, including chemical resistant gloves, eye protection, and a protective smock.
Before handling with 3,4-difluoronitrobenzene, thoroughly here review the material safety data sheet (MSDS) provided by the manufacturer. This guide will provide detailed guidance on potential risks, first aid, and preservation procedures.
- Steer clear of interaction with eyes. In the event of exposure, promptly flush the region with plenty of clean water for at least fifteen minutes.
- Preserve 3,4-difluoronitrobenzene in a tempered location away from heat sources and hazardous compounds.
- Eliminate of 3,4-difluoronitrobenzene properly in accordance with environmental guidelines.
Spectral Characterization of 3,4-Difluoronitrobenzene
The spectral characterization of DFNB is crucial for comprehending its chemical properties and potential applications.
IR|UV-Vis|NMR spectroscopy provides valuable insight into the vibrational modes, electronic transitions, and nuclear structure of this compound.
The characteristic spectral features observed may be assigned to the presence of the nitro group, fluorine atoms, and benzene ring. Further spectral analysis reveals the influence of these substituents on the overall molecular polarity.
This thorough spectral characterization enhances our appreciation of DFNB and its potential role in various chemical systems.